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1. Basic Properties
Product Name: Natamycin
CAS Number: 7681-93-8
Molecular Formula: C33H47NO13
Molecular Weight: 665.73
EINECS Number: 231-683-5
Category: Polyene Macrolide
2. Physical Properties
·Appearance: Natamycin is a near-white or cream-yellow crystalline powder, odorless and tasteless.
·Solubility: It is practically insoluble in water, slightly soluble in methanol, and soluble in glacial acetic acid and dimethyl sulfoxide (DMSO). Its solubility increases at pH values higher than 9 or lower than 3.
·Stability: Natamycin is relatively stable in dry form and can withstand short-term high temperatures (up to 100°C). However, due to its cyclic chemical structure, it is sensitive to ultraviolet light and should not be exposed to sunlight. Additionally, natamycin is highly sensitive to oxidizing agents.
3. Chemical Properties
·Natamycin has a polyene planar macrolide structure. The conjugated double bonds interact through van der Waals forces with ergosterol or other sterol groups in fungi, forming a natamycin-ergosterol complex. This interaction causes distortion in the fungal cell membrane, altering its permeability and leading to leakage of essential intracellular substances, such as amino acids, ultimately resulting in cell death.
- Product Details
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